| Name
|
Gastrin-1, Human
|
| Other Name
|
Gastrin1; [18-Pyroglutamic acid]big gastrin I-(18-34)-peptide amide, human[pGlu18]-Big gastrin fragment 18-34 amide gastrin I, heptadecapeptide
|
| Sequence (Single letter abbreviations)
|
PyrGPWLEEEEEAYGWMDF-NH2
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| Sequence（Three letter abbreviations）
|
{pGLU}{GLY}{PRO}{TRP}{LEU}{GLU}{GLU}{GLU}{GLU}{GLU}{ALA}{TYR}{GLY}{TRP}{MET}{ASP}{PHE}-NH2
|
| C-port
|
NH2
|
| Basic description
|
Gastrin-1 (human), which is mainly expressed in the gut, activates gastric acid secretion and stimulates lectin-like protein Reg expression via activation of PKC and RhoA. It is used as a marker for gastritis.
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| Solubility
|
The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
|
| The molecular weight
|
2098.210
|
| Chemical formula
|
C97H124N20O31S
|
| The purity
|
> 95%
|
| Storage conditions
|
Store the peptide at -20°C. Keep container tightly closed.
|
| Annotation
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| Documents
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| Figures
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| Reference
|
Clarke PA, et al. Gastrin enhances the angiogenic potential of endothelial cells via modulation of heparin-binding epidermal-like growth factor. Cancer Res. Apr 2006; 66(7): 3504-3512.
Jain RN, et al. Gene expression profiling of gastrin target genes in parietal cells. Physiol. Genomics. Jan 2006; 24(2): 124-312.
Kanda N, et al. Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice. Am. J. Physiol. Gastrointest. Liver Physiol. Mar 2006; 290(3): G519-G527.
Tianbing Liu and Pedro A. Jose.., etc. Gastrin Induces Sodium-Hydrogen Exchanger 3 Phosphorylation and mTOR Activation via a Phosphoinositide 3-Kinase-/Protein Kinase C-Dependent but AKT-Independent Pathway in Renal Pro
Yu H., etc. Epidermal Growth Factor and Gastrin on PDX1 Expression in Experimental Type 1 Diabetic Rats. Am J Med Sci. 2012 Feb;343(2):141-5.
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Gastrin-1, Human
