Name
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Gly-Arg-Gly-Asp-Ser
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Other Name
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GRGDD; GLY-ARG-GLY-ASP-SER
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Sequence (Single letter abbreviations)
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GRGDS
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Sequence(Three letter abbreviations)
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{GLY}{ARG}{GLY}{ASP}{SER}
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Basic description
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The synthetic peptide Gly-Arg-Gly-Asp-Ser (GRGDS) mimics the cellular binding site of many adhesive proteins in the extracellular matrix and causes rounding and detachment of spread cells. The GRGDS (Gly-Arg-Gly-Asp-Ser) peptide has intermediate affinity to V3 and IIb3, which are the integrins more reported to be involved in bone function.
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The molecular weight
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490.500
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Chemical formula
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C17H30N8O9
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The purity
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> 95%
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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Le Saux G., etc. The relative importance of topography and RGD ligand density for endothelial cell adhesion. PLoS One. 2011 Jul;6(7):e21869.
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