| Name
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Ghrelin, Rat
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| Other Name
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| Sequence (Single letter abbreviations)
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GSS(n-Octanoyl)FLSPEHQKAQQRKESKKPPAKLQPR
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| Sequence（Three letter abbreviations）
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{Gly}{Ser}{Ser}(n-octanoyl){The}{Leu}{Ser}{Pro}{Glu}{His}{Gln}{Lys}{Ala}{Gln}{Gln}{Arg}{Lys}{Glu}{Ser}{Lys}{Lys}{Pro}{Pro}{Ala}{Lys}{Leu}{Gln}{Pro}{Arg}
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| Basic description
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Ghrelin is the first natural appetite stimulant found to be made outside the brain. It is one of a complex array of natural substances that carry messages between the brain and the digestive system. Secreted by specialized cells in the stomach and the upper part of the small intestine, ghrelin acts on the brain. The hormone ghrelin is produced at levels in the stomach when the organism is hungry and at decreased levels after meals. As such, this hormone plays a critical role in signaling the brain and has become an important focus of obesity research.
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| The molecular weight
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3314.800
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| Chemical formula
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C147H245N45O42
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| The purity
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> 95%
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| Storage conditions
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Store the peptide at -20°C. Keep container tightly closed.
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| Annotation
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| Documents
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| Figures
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| Reference
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Dixit VD, et al. Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility. J. Biol. Chem. Jun 2006; 281(24): 16681-16690.
Gauna C, ,i>et al. Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor. Mol. Cell Endocrinol. Jun 2006; 251(1-2): 103-111.
M R McFarlane et al Induced Ablation of Ghrelin Cells in Adult Mice Does Not Decrease Food Intake, Body Weight, or Response to -Fat Diet. Cell Metab 2014 Jul; 20 (1); 54-60
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Ghrelin, Rat
