Name
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EGFRvIII Peptide (PEPvIII)
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Sequence (Single letter abbreviations)
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LEEKKGNYVVTDHC
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Sequence(Three letter abbreviations)
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{Leu}{Glu}{Glu}{Lys}{Lys}{Gly}{Asn}{Tyr}{Val}{Val}{Thr}{Asp}{His}{Cys}
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Basic description
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The epidermal growth factor receptor variant III (EGFRvIII) is a consistent tumor-specific mutation that is widely expressed in glioblastoma multiforme (GBM) and other neoplasms. As such it represents a truly tumor-specific target for antitumor immunotherapy.
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The molecular weight
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1634.820
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Chemical formula
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C31H45N6O17P
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The purity
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> 95%
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Storage conditions
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Store at -20°C.
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Documents
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Figures
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Reference
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Expert Opin Biol Ther. 2009 Aug;9(8):1087-98.Author:Heimberger AB.
J Immunol Methods. 2008 Nov 30;339(1):74-81. Epub 2008 Sep 4.Author:Schmittling RJ.
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