| Name
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EGFR (988-993) (Phospho-Tyr5)
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| Sequence (Single letter abbreviations)
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DADE-pY-L
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| Sequence（Three letter abbreviations）
|
{Asp}{Ala}{Asp}{Glu}{pTyr}{Leu}
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| Basic description
|
This phosphotyrosil peptide sequence is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). Using synthetic pTyr-containing peptides that correspond to natural phosphorylation sites in proteins, several groups have demonstrated that PTPases display a range of kcat/Km values for these relatively short peptide substrates. This peptide is a minimal (6 residues) peptide substrate for both the Yersinia PTPase and the mammalian PTP1. It is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B).
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| The molecular weight
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804.700
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| Chemical formula
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C31H45N6O17P
|
| The purity
|
> 95%
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| Storage conditions
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Store at -20°C.
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| Reference
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| Documents
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EGFR (988-993) (Phospho-Tyr5)
