| Name
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Calcineurin Substrate
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| Other Name
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|
| Sequence (Single letter abbreviations)
|
DLDVPIPGRFDRRVSVAAE
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| Sequence（Three letter abbreviations）
|
{ASP}{LEU}{ASP}{VAL}{PRO}{ILE}{PRO}{GLY}{ARG}{PHE}{ASP}{ARG}{ARG}{VAL}{SER}{VAL}{ALA}{ALA}{GLU}
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| Basic description
|
Calcineurin Substrate is a Peptide from the regulatory RII subunit of cAMP-dependent protein kinase. Calcineurin Substrate is useful in assays for protein phosphatase-2B (calcineurin) activity.
|
| The molecular weight
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2112.400
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| Chemical formula
|
C92H150N28O29
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| The purity
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> 95%
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| Storage conditions
|
Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 24 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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| Annotation
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This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
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| Documents
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| Figures
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| Reference
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Bultynck G, et al. Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Mol. Cell. Biol. Jun 2006; 26(12): 4729-4745.
Torgan CE, Daniels MP. Calcineurin localization in skeletal muscle offers insights into potential new targets. J. Histochem. Cytochem. Jan 2006; 54(1): 119-128.
Buch MH, et al. The sarcolemmal calcium pump inhibits the calcineurin/nuclear factor of activated T-cell pathway via interaction with the calcineurin A catalytic subunit. J. Biol. Chem. Aug 2005; 280(33): 29479-29487.
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Calcineurin Substrate
