| Name
|
C-Type Natriuretic Peptide (CNP) (1-22), Human
|
| Other Name
|
CNP (1-22), humanCNP
|
| Sequence (Single letter abbreviations)
|
GLSKGCFGLKLDRIGSMSGLGC
|
| Sequence（Three letter abbreviations）
|
{GLY}{LEU}{SER}{LYS}{GLY}{CYS}{PHE}{GLY}{LEU}{LYS}{LEU}{ASP}{ARG}{ILE}{GLY}{SER}{MET}{SER}{GLY}{LEU}{GLY}{CYS}
|
| Chemical bridge
|
Disulfide bridge: Cys6-Cys22
|
| Basic description
|
C-type natriuretic peptide is produced in the hypothalamus, anterior pituitary, and more major endocrine glands. C-type natriuretic peptide has potent venodilatory and coronary vasodilatory effects, but minimal effects on renal function.
|
| Solubility
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
|
| The molecular weight
|
2197.600
|
| Chemical formula
|
C93H157N27O28S3
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C.
|
| Annotation
|
Pharmacological spectrum similar to ANP and BNP.
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| Documents
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| Figures
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| Reference
|
Anderson WG, et al. The effects of freshwater to seawater transfer on circulating levels of angiotensin II, C-type natriuretic peptide and arginine vasotocin in the euryhaline elasmobranch, Carcharhinus leucas. Gen. Comp. Endocrinol. May 2006; 147(1): 39-46.
Yeh LC, et al. C-type natriuretic peptide enhances osteogenic protein-1-induced osteoblastic cell differentiation via Smad5 phosphorylation. J. Cell. Biochem. Feb 2006; 97(3): 494-500.
Hong TC, et al. Brain natriuretic peptide and C-type natriuretic peptide are differently regulated by age but similarly elevated in coronary artery disease. Acta. Cardiol. Feb 2006; 61(1): 1-5.
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C-Type Natriuretic Peptide (CNP) (1-22), Human
