Name
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C-Telopeptide
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Other Name
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CTX
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Sequence (Single letter abbreviations)
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EKAHDGGR
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Sequence(Three letter abbreviations)
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{GLU}{LYS}{ALA}{HIS}{ASP}{GLY}{GLY}{ARG}
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Basic description
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C-telopeptide(CTX) is an RIA based on monoclonal antibody raised against this 8-amino-acid sequence was developed. C-telopeptide(CTX) represents a valuable tool for assessing bone resorption. The study shows C-telopeptide(CTX) ELISA exhibited acceptable analytical performance and sufficient discriminatory power to show expected directional changes in the rate of bone resorption following ovariectomy, ovx plus estradiol or alendronate treatment, and administration of a calcium-deficient diet.
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The molecular weight
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868.900
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Chemical formula
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C34H56N14O13
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纯度
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> 95%
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The purity
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Store at -20°C.
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Annotation
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Documents
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Figures
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Reference
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Garnero P, et al. Increased urinary type II collagen helical (Helix-II) and C-telopeptide(CTX-II) levels are independently associated with a rapidly destructive hip osteoarthritis. Ann. Rheum. Dis. Mar 2006.
Mazzuca SA, et al. Urinary Levels of Type II Collagen C-telopeptide Crosslink Are Unrelated to Joint Space Narrowing in Patients With Knee Osteoarthritis. Ann. Rheum. Dis. Dec 2005.
Alexandersen P, et al. Non-isomerized C-telopeptide fragments are ly sensitive markers for monitoring disease activity and treatment efficacy in Paget's disease of bone. J. Bone Miner. Res. Apr 2005; 20(4): 588-595.
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