| Name
|
Competence-Stimulating Peptide-12261
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| Sequence (Single letter abbreviations)
|
EIRQTHNIFFNFFKRR
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| Sequence（Three letter abbreviations）
|
{Glu}{Ile}{Arg}{Gln}{Thr}{His}{Asn}{Ile}{Phe}{Phe}{Asn}{Phe}{Phe}{Lys}{Arg}{Arg}
|
| Basic description
|
Bacteria are capable of natural genetic transformation especially when they are under external selection pressure including vaccination or antibiotics treatment. The capability of the genetic transformation in Streptococcus pneumoniae,Streptococcus mitis and Streptococcus oralis are controlled by secreted peptide pheromones named Competence-Stimulating Peptide . Different strains and species of these bacteria produce CSP with different primary sequence. They are termed pheromones CSP-1 , CSP-2 (EMRISRIILDFLFLRKK), CSP-153 (DKRLPYFFKHLFSNRTK), CSP-612 (ESRLSRLLRDFIFQIKQ), CSP-676 (ERRIPDVIRSLLFQKRK), and CSP-12261 (EIRQTHNIFFNFFKRR).
|
| The molecular weight
|
2153.500
|
| Chemical formula
|
C100H149N31O23
|
| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Documents
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|
| Figures
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|
| Reference
|
Johnsborg O,Mol Microbiol. 2008 Jul;69(1):245-53. Epub 2008 May 15.
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Competence-Stimulating Peptide-12261
