Name
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C-Myc Peptide
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Sequence (Single letter abbreviations)
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EQKLISEEDL
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Sequence(Three letter abbreviations)
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{GLU}{GLN}{LYS}{LEU}{ILE}{SER}{GLU}{GLU}{ASP}{LEU}
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Basic description
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c-Myc Peptide is a useful for displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific. c-Myc Peptide participates in regulation of growth-related gene transcription.
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Solubility
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Soluble in PBS, pH 7.0. The optimal working dilution should be determined for each specific assay condition.
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The molecular weight
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1203.300
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Chemical formula
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C51H86N12O21
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The purity
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> 95%
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Storage conditions
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Store at -20°C. Keep tightly closed.
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Annotation
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Amino acid sequence of c-Myc Peptide is corresponds to amino acids 410-419 of the C-terminal of human c-Myc. This peptide is sold for laboratory research use only, not for human or in-vivo use. This peptide may not be resold or modified for resale without prior written approval.
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Documents
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Figures
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Reference
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Lee AS, et al. A novel capture-ELISA for detection of anti-neutrophil cytoplasmic antibodies (ANCA) based on c-myc peptide recognition in carboxy-terminally tagged recombinant neutrophil serine proteases. J. Immunol. Methods. Dec 2005; 307(1-2): 62-72.
Saini N., etc. Fragile DNA Motifs Trigger Mutagenesis at Distant Chromosomal Loci in Saccharomyces cerevisiae. PLoS Genet. 2013 Jun;9(6):e1003551.
Chen S., etc. RAD6 regulates the dosage of p53 by a combination of transcriptional and posttranscriptional mechanisms. Mol Cell Biol. 2012 Jan;32(2):576-87.
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