Name
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Calcitonin Gene Related Peptide (CGRP), Rat
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Other Name
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CGRP, ratCGRP-I;α-CGRP
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Sequence (Single letter abbreviations)
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SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2
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Sequence(Three letter abbreviations)
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{SER}{CYS}{ASN}{THR}{ALA}{THR}{CYS}{VAL}{THR}{HIS}{ARG}{LEU}{ALA}{GLY}{LEU}{LEU}{SER}{ARG}{SER}{GLY}{GLY}{VAL}{VAL}{LYS}{ASP}{ASN}{PHE}{VAL}{PRO}{THR}{ASN}{VAL}{GLY}{SER}{GLU}{ALA}{PHE}-NH2
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C-port
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NH2
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Chemical bridge
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Disulfide Bridge: Cys2-Cys7
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Basic description
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Calcitonin Gene Related Peptide (rat) is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
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Solubility
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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The molecular weight
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3806.250
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Chemical formula
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C162H262N50O52S2
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The purity
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> 95%
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Storage conditions
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Before using, store the peptide in the DRY form at 0-5°C. For and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
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Annotation
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Documents
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Figures
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Reference
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Rapp DE, et al. Botulinum toxin type a inhibits calcitonin gene-related peptide release from isolated rat bladder. J. Urol. Mar 2006; 175(3 Pt 1): 1138-1142.
Chai W, et al. The role of calcitonin gene-related peptide (CGRP) in ischemic preconditioning in isolated rat hearts. Eur. J. Pharmacol. Feb 2006; 531(1-3): 246-253.
Fernihough J, et al. Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis. Neurosci. Lett. Nov 2005; 388(2): 75-80.
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