Name
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Bak bh3
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Other Name
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Bak BH3
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Sequence (Single letter abbreviations)
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GQVGRQLAIIGDDINR
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Sequence(Three letter abbreviations)
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{Gly}{Gln}{Val}{Gly}{Arg}{Gln}{Leu}{Ala}{Ile}{Ile}{Gly}{Asp}{Asp}{Ile}{Asn}{Arg}
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Basic description
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This peptide, generated from the BH3 domain of Bak (Flu-BakBH3), has been shown to have -affinity binding to a surface pocket of the Bcl-XL protein that is required for its death antagonist function.
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The molecular weight
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1724.900
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Chemical formula
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C72H125N25O24
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The purity
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> 95%
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Storage conditions
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Store the peptide at -20°C.
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N-port
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Abz/DNP
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Documents
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Figures
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Reference
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Ku B., et al. Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX. Cell Res. 2011 Apr;21(4):627-41.
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