Name
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Abz-LPETG-K(Dnp)-NH2
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Other Name
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Sequence (Single letter abbreviations)
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Abz-LPETG-K(Dnp)-NH2
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Sequence(Three letter abbreviations)
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Abz-{Leu}{Pro}{Glu}{Thr}{Gly}{Lys(Dnp)}-NH2
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C-port
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Amidation
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Basic description
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The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges.
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The molecular weight
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928.000
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Chemical formula
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C41H57N11O14
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The purity
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> 95%
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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N-port
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Abz/DNP
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Documents
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Figures
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Reference
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Bentley ML,J Biol Chem. 2007 Mar 2;282(9):6571-81. Epub 2007 Jan 2.
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