Name
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Adipokinetic Hormone (AKH), Locust
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Other Name
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Sequence (Single letter abbreviations)
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Sequence(Three letter abbreviations)
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GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2
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C-port
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NH2
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Basic description
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Adipokinetic hormones (AKHs) are metabolic neuropeptides, mediating mobilization of energy substrates from the fat body in many insects. They bring on the release of diglycerides and then stimulate the flight muscles to use them as an energy source. There are other types of active peptides structurally related to AKH. These peptides are eight to ten amino acid residues long.
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The molecular weight
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1159.400
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Chemical formula
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C54H74N14O15
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The purity
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> 95%
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Storage conditions
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Store at -20°C
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Annotation
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Documents
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Figures
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Reference
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Isabel G, et al. AKH-producing neuroendocrine cell ablation decreases trehalose and induces behavioral changes in Drosophila. Am. J. Physiol. Regul. Integr. Comp. Physiol. Feb 2005; 288(2): R531-R538.
Wicher D, et al. Differential receptor activation by cockroach adipokinetic hormones produces differential effects on ion currents, neuronal activity, and locomotion. J. Neurophysiol. Apr 2006; 95(4): 2314-25.
Goldsworthy GJ, et al. Adipokinetic hormone and the immune responses of locusts to infection. Ann. N. Y. Acad. Sci. Apr 2005; 1040: 106-13.
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