| Name
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Autocamtide 2
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| Other Name
|
Autocamtide2; AC-2; AC2
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| Sequence (Single letter abbreviations)
|
KKALRRQETVDAL
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| Sequence（Three letter abbreviations）
|
{LYS}{LYS}{ALA}{LEU}{ARG}{ARG}{GLN}{GLU}{THR}{VAL}{ASP}{ALA}{LEU}
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| Basic description
|
The native peptide Autocamtide 2 (KKALRRQETVDAL) is a ly selective substrate for Ca2+/calmodulin-dependent protein kinase (CaMK). The peptide Autocamtide 2 contains the sequence around the autophosphorylation site in the autoinhibitory domain of calmodulin-dependent protein kinase II (CaM kinase II). The fluorescent and biotinylated peptides are used to design assays for CaMKs.
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| Solubility
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
|
| The molecular weight
|
1527.770
|
| Chemical formula
|
C65H118N22O20
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| The purity
|
> 95%
|
| Storage conditions
|
Store at -20°C
|
| Annotation
|
ly selective substrate for CaM kinase used for Ca2+/Calmodulin-dependent Protein Kinase studies.
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| Documents
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| Figures
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| Reference
|
Aromolaran AA, Blatter LA. Modulation of intracellular Ca2+ release and capacitative Ca2+ entry by CaMKII inhibitors in bovine vascular endothelial cells. Am. J. Physiol., Cell Physiol. Dec 2005; 289(6): C1426-C1436.
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Autocamtide 2
