Name
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Atrial Natriuretic Peptide (ANP) (1-28), Human, Porcine
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Other Name
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ANP (1-28), human, porcineANP(1-28)
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Sequence (Single letter abbreviations)
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SLRRSSCFGGRMDRIGAQSGLGCNSFRY (Disulfide bridge: 7-23)
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Sequence(Three letter abbreviations)
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{SER}{LEU}{ARG}{ARG}{SER}{SER}{CYS}{PHE}{GLY}{GLY}{ARG}{MET}{ASP}{ARG}{ILE}{GLY}{ALA}{GLN}{SER}{GLY}{LEU}{GLY}{CYS}{ASN}{SER}{PHE}{ARG}{TYR}
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Chemical bridge
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7-23
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Basic description
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Atrial natriuretic peptide (ANP), a stimulator of particulate guanylate cyclase, has been found to protect against reoxygenation-induced hypercontracture in isolated cardiomyocytes by increasing cyclic guanosine monophosphate synthesis; ANP also contributes to stimulation of lipolysis during repeated bouts of exercise and in the control of lipolysis during exercise.
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Solubility
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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The molecular weight
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3080.500
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Chemical formula
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C128H205N45O39S2
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The purity
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> 95%
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Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Annotation
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Documents
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Figures
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Reference
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Zhang M, et al. The expression of atrial natriuretic peptide in the oviduct and its functions in pig spermatozoa. J. Endocrinol. Jun 2006; 189(3): 493-507.
Muller D, et al. Homologous and lysophosphatidic acid-induced desensitization of the atrial natriuretic peptide receptor, guanylyl cyclase-A, in MA-10 leydig cells. Endocrinology. Jun 2006; 147(6): 2974-2985.
Toma I, et al. Intrapericardial angiotensin II stimulates endothelin-1 and atrial natriuretic peptide formation of the in situ dog heart. Exp. Biol. Med(Maywood). Jun 2006; 231(6): 847-851.
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