| Name
|
Adrenocorticotropic Hormone (ACTH) (1-24), Human
|
| Other Name
|
ACTH (1-24), humanAdrenocorticotropic Hormone Fragment 1-24, human; Tetracosactide
|
| Sequence (Single letter abbreviations)
|
SYSMEHFRWGKPVGKKRRPVKVYP
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| Sequence（Three letter abbreviations）
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{SER}{TYR}{SER}{MET}{GLU}{HIS}{PHE}{ARG}{TRP}{GLY}{LYS}{PRO}{VAL}{GLY}{LYS}{LYS}{ARG}{ARG}{PRO}{VAL}{LYS}{VAL}{TYR}{PRO}
|
| Basic description
|
Adrenocorticotropic hormones (ACTH). ACTH stimulates the adrenal cortex and the secretion of glucocorticoids such as cortisol. Another name for ACTH is corticotropin. ACTH (1-24) activates G proteins.
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| Solubility
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
|
| The molecular weight
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2933.440
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| Chemical formula
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C136H210N40O31S1
|
| The purity
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> 95%
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| Storage conditions
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Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place.
|
| Annotation
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The portion of the ACTH sequence that is conserved across species has ≈75% of the potency of ACTH on a molar basis.
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| Documents
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| Figures
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| Reference
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Yoshida-Hiroi M, et al. Intranasal administration of ACTH(1-24) stimulates catecholamine secretion. Horm. Metab. Res. Aug 2005; 37(8): 489-493.
Zwermann O, et al. ACTH 1-24 inhibits proliferation of adrenocortical tumors in vivo. Eur. J. Endocrinol. Sep 2005; 153(3): 435-444.
Jensen SM., etc. Differential Inhibitory Effects of Cyanovirin-N, Griffithsin and Scytovirin on Entry Mediated by Envelopes of Gammaretroviruses and Deltaretroviruses. J Virol. 2013 Nov.
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Adrenocorticotropic Hormone (ACTH) (1-24), Human
