Name
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Rabbit Anti-AMPK beta 2 Antibody
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Basic description
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PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
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Character
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Lyophilized or Liquid
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Purification methods
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affinity purified by Protein A or Protein G
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Storage of liquid
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0.01M PBS(pH7.4) with 1% BSA。
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Storage conditions
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Store at -20°C.
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Subtypes
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IgG
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