Name
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Rabbit Anti-Girdin Antibody
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Basic description
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This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Character
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Lyophilized or Liquid
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Purification methods
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affinity purified by Protein A or Protein G
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Storage of liquid
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0.01M PBS(pH7.4) with 1% BSA。
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Storage conditions
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Store at -20°C.
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Subtypes
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IgG
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