Name
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Rabbit Anti-ANGPTL3 Antibody
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Basic description
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Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
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Character
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Lyophilized or Liquid
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Purification methods
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affinity purified by Protein A or Protein G
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Storage of liquid
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0.01M PBS(pH7.4) with 1% BSA。
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Storage conditions
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Store at -20°C.
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Subtypes
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IgG
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