Name
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Rabbit Anti-alpha Adducin Antibody
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Chinese name
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内收蛋白a1抗体
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Basic description
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Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-Actin junction of the membrane skeleton. The cortical Actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical Actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta . Adducin beta is expressed at levels in brain and hematopoietic tissues, such as bone marrow in humans and spleen in mice.
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Antibody type
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rabbit polyclonal antibodies
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Immune to the original
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Coupling peptides or recombinant protein
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Concentration
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1mg/ml
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Storage conditions
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Store at -20°C.
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Subtypes
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IgG
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Composition
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Affinity purification,0.01M PBS(pH7.4),1% BSA
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Application
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WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500
IF=1:100-500
optimal dilutions/concentrations should be determined by the end user.
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