| Name
|
Rabbit Anti-ARHGAP24 Antibody
|
| Basic description
|
ARHGAP24 is a rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. It acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. It controls actin remodeling by inactivating Rac downstream of Rho to suppress edge protrusion and promotes cell retraction to achieve cellular polarity. There are five different isoforms.Isoform 1 is widely expressed with a er level in kidney. Isoform 2 is mainly expressed in endothelial cells and is involved in modulation of angiogenesis.
|
| Antibody type
|
rabbit polyclonal antibodies
|
| Immune to the original
|
Coupling peptides or recombinant protein
|
| Concentration
|
1mg/ml
|
| Storage conditions
|
Store at -20°C.
|
| Subtypes
|
IgG
|
| Composition
|
Affinity purification，0.01M PBS(pH7.4)，1% BSA
|
| Application
|
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500
IF=1:100-500
optimal dilutions/concentrations should be determined by the end user.
|
Rabbit Anti-ARHGAP24 Antibody/Rho GTP酶激活蛋白24抗体
