| Name
|
Rabbit Anti-ARP4 Antibody
|
| Chinese name
|
血管生成素样蛋白4抗体
|
| Basic description
|
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
|
| Antibody type
|
rabbit polyclonal antibodies
|
| Immune to the original
|
Coupling peptides or recombinant protein
|
| Concentration
|
1mg/ml
|
| Storage conditions
|
Store at -20°C.
|
| Subtypes
|
IgG
|
| Composition
|
Affinity purification，0.01M PBS(pH7.4)，1% BSA
|
| Application
|
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500
IF=1:100-500
optimal dilutions/concentrations should be determined by the end user.
|
Rabbit Anti-ARP4 Antibody/血管生成素样蛋白4抗体
