Custom Peptide Synthesis,Peptide,Custom Peptide,peptide synthesis- ChinaPeptides

Name	Rabbit Anti-A4GALT Antibody
Chinese name	α1,4-半乳糖基转移酶1
Basic description	Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.Expression of CD77, also called Gb3, sensitizes a cell to verotoxins, causing cellular injury that can lead to disease. Therefore, the complex regulation of CD77 biosynthesis and the activity of the enzymes involved, such as CD77 synthase, can be studied by compared gene expression between toxin-sensitive and insensitive tissues and cell lines. The tissue expression of CD77 synthase occurs in the kidney, mesenteric lymph node, spleen, and brain. Burkitt leukemia cells express very levels of CD77 as well as CD77 synthase, and are sensitive to verotoxin induced apoptosis. These megakaryoblasts then never mature, to the arrest of platelet generation in the bone marrow, which may cause thrombocytopenia, a symptom associated with various hemorrhagic conditions.
Antibody type	rabbit polyclonal antibodies
Immune to the original	Coupling peptides or recombinant protein
Concentration	1mg/ml
Storage conditions	Store at -20°C.
Subtypes	IgG
Composition	Affinity purification，0.01M PBS(pH7.4)，1% BSA
Application	WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 optimal dilutions/concentrations should be determined by the end user.