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Name	Rabbit Anti-ANT-1 Antibody
Basic description	Defects in SLC25A4 are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 2 (PEOA2) [MIM:609283]. Progressive external ophthalmoplegia is characterized by progressive weakness of ocular muscles and levator muscle of the upper eyelid. In a minority of cases, it is associated with skeletal myopathy, which predominantly involves axial or proximal muscles and which causes abnormal fatigability and even permanent muscle weakness. Ragged-red fibers and atrophy are found on muscle biopsy. A large proportion of chronic ophthalmoplegias are associated with other symptoms, to a multisystemic pattern of this disease. Additional symptoms are variable, and may include cataracts, hearing loss, sensory axonal neuropathy, ataxia, depression, hypogonadism, and parkinsonism.
Antibody type	rabbit polyclonal antibodies
Immune to the original	Coupling peptides or recombinant protein
Concentration	1mg/ml
Storage conditions	Store at -20°C.
Subtypes	IgG
Composition	Affinity purification，0.01M PBS(pH7.4)，1% BSA
Application	WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 optimal dilutions/concentrations should be determined by the end user.