Name
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Rabbit Anti-Ack1 Antibody
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Basic description
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This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
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Character
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Lyophilized or Liquid
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Purification methods
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affinity purified by Protein A or Protein G
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Storage of liquid
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0.01M PBS(pH7.4) with 1% BSA。
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Storage conditions
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Store at -20°C.
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Subtypes
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IgG
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