Name
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Human aFGF / FGF1 Protein
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Basic description
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aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.
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Molecular nickname
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aFGF, FGF1, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1
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Molecular species
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Human
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Express label
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His,S
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Expression of the host
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E. coli
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The purity
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> 95 % as determined by SDS-PAGE
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Buffer
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Lyophilized from sterile PBS, pH 7.4
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Save method
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-70°C,Avoid repeated freezing and thawing。
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