名称
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M13 Skeletal Muscle Myosin Light Chain Kin
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编码
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别名
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M13 Skeletal Muscle Myosin Light Chain Kin
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纯度
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80%,90%,95%,98%,99%
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重量
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1mg,5mg,10mg,50mg,100mg,1g
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序列(单字母缩写)
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KRRWKKNFIAVSAANRFKKISSSGAL
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序列(三字母缩写)
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H-Lys-Arg-Arg-Trp-Lys-Lys-Asn-Phe-Ile-Ala-Val-Ser-Ala-Ala-Asn-Arg-Phe-Lys-Lys-Ile-Ser-Ser-Ser-Gly-Ala-Leu-OH (trifluoroacetate salt)
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基本描述
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This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1伪 (IL-1伪) in response to P2X7R activation.
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溶解度
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分子量
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2964.5
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化学式
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C134H223N43O33
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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注释
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Documents
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Figures
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Reference
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Johnson, D. et al. J. Biol. Chem. 271, 761 (1996)
Lee, W. et al. J. Biol. Chem. 278, 25940 (2003)
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C端
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N端
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化学桥
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