| 名称
|
RGD-4C
|
| 编码
|
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| 别名
|
RGD-4C
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| 纯度
|
80%，90%，95%，98%，99%
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| 重量
|
1mg,5mg,10mg,50mg,100mg,1g
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| 序列（单字母缩写）
|
ACDCRGDCFCG (Disulfide bridge: 2-10 and 4-8)
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| 序列（三字母缩写）
|
H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH (trifluoroacetate salt)(Disulfide bridge: 2-10 and 4-8)
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| 基本描述
|
This sequence is a targeted proapoptotic peptide. The C-terminal RGD-4C peptide (ACDCRGDCFC) binds preferentially to integrins at sites of tumor angiogenesis. Two glycines provide spacer, and D(KLAKLAK)2 is the proapoptotic peptide composed of D-amino acids.
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| 溶解度
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|
| 分子量
|
1145.3
|
| 化学式
|
C42H60N14O16S4
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| 存储条件
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| 注释
|
|
| Documents
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| Figures
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| Reference
|
Curnis, F. et al. Cancer Res. 64, 565 (2004)
Su, Z. et al. Bioconjug. Chem. 13, 561 (2002)
Gerlag, M. et al. Arthritis Res. 3, 357 (2001)
Ellerby, H. et al. Nature Med. 5, 1032 (1999)
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| C端
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| N端
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| 化学桥
|
(Disulfide bridge: 2-10 and 4-8)
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