名称
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Caspase 8 Substrate 1, chromogenic
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编码
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别名
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Caspase 8 Substrate 1, chromogenic
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纯度
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80%,90%,95%,98%,99%
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重量
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1mg,5mg,10mg,50mg,100mg,1g
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序列(单字母缩写)
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Ac-IETD-pNA
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序列(三字母缩写)
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Ac-Ile-Glu-Thr-Asp-pNA
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基本描述
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pNA (4-nitroaniline)-derived caspase substrates widely used for various caspase activities and colorimetric detection. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm. Caspase-9 substrate.
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溶解度
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分子量
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638.6
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化学式
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C27H38N6O12
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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注释
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Documents
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Figures
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Reference
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Grutter MG (2000) Curr Opin Struct Biol 10, 649-55
Gastman BR (2001) Head Neck 23, 409-25
Grutter MG (2000) Curr Opin Struct Biol 10, 649-55
Stennicke HR and Salvesen GS (1999)Cell Death Differ 6, 1054-9
Stennicke HR and Salvesen GS (1998) Biochim Biophys Acta 1387, 17-31
Thornberry NA and Lazebnik Y (1998) Science 281, 1312-6
Talanian RV, et al. (1997) . J Biol Chem 272, 9677-82.
Fassy F, et al. (1998) Eur J Biochem 253, 76-83
Datta R, et al. (1996) Blood 88, 1936-43
Koeplinger KA, et al. (2000) Protein Expr Purif 18, 378-87
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C端
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N端
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化学桥
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