目录多肽

名称 Amyloid beta-Protein (25-35)
编码 [131602-53-4]
别名 Amyloid beta-Protein (25-35)
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） GSNKGAIIGLM
序列（三字母缩写） H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH (trifluoroacetate salt)
基本描述 This peptide was isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. It is the fragment (61-95) of NACP or alpha-synuclein and forms amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.
溶解度
分子量 1060.28
化学式 C45H81N13O14S1
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
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Reference B.A.Yankner et al., Science, 250, 279 (1990) A.Klegeris et al., Biochem. Biophys. Res. Commun., 199, 984 (1994) C.J.Pike et al., Neuroscience, 63, 517 (1994) C.J.Pike et al., J. Neurochem., 64, 253 (1995) J.H.Ippel et al., Proc. Natl. Acad. Sci. USA, 99, 8648 (2002) M.E.Clementi et al., FEBS Lett., 579, 2913 (2005) F.Misiti et al., Neurochem. Int., 46, 575 (2005) G.Wei and J.-E.Shea, Biophys. J., 91, 1638 (2006) D.Buntup et al., Neurochem. Res., 33, 248 (2008) I.D.Limon et al., Neurosci. Res., 63, 129 (2009) L.Millucci et al., Curr. Protein Pept. Sci., 11, 54 (2010) H.-H.G.Tsai et al., Proteins, 78, 1909 (2010)
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