名称
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Beta-Sheet Breaker Peptide iAbeta5p,[Pro18, Asp21]-?-Amyloid (17-21), iAb5
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编码
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[182912-74-9]
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别名
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Beta-Sheet Breaker Peptide iAbeta5p,[Pro18, Asp21]-?-Amyloid (17-21), iAb5
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纯度
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80%,90%,95%,98%,99%
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重量
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1mg,5mg,10mg,50mg,100mg,1g
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序列(单字母缩写)
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LPFFD
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序列(三字母缩写)
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H-Leu-Pro-Phe-Phe-Asp-OH (trifluoroacetate salt)
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基本描述
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beta-sheet breaker peptide iAbeta5p that crosses the blood-brain barrier at a higher rate than most proteins and peptides. It is known to be selectively taken up by the brain, thereby suggesting that the peptide is being specifically transported to the brain. A significant increase in neuronal survival and decrease in brain inflammation associated with the reduction of amyloid plaques in two different transgenic Alzheimer's disease (AD) models is additionally reported for this pentapeptide. Abeta (1-42) Fibrillogenesis Inhibitor.
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溶解度
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分子量
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637.7
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化学式
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C33H43N5O8
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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注释
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Documents
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Figures
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Reference
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C端
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N端
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化学桥
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