名称
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2 CDC25C, CHK1 and CHK2 Substrate, phospho
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编码
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别名
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2 CDC25C, CHK1 and CHK2 Substrate, phospho
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纯度
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80%,90%,95%,98%,99%
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重量
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1mg,5mg,10mg,50mg,100mg,1g
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序列(单字母缩写)
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KKKVSRSGLYR-pS-PSMPENLNRPR-NH2
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序列(三字母缩写)
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H-Lys-Lys-Lys-Val-Ser-Arg-Ser-Gly-Leu-Tyr-Arg-pSer-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg-NH2?(trifluoroacetate salt)
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基本描述
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The native peptide ARKRERTYSFGHHA (29944-1) is a synthetic substrate for AKT/PKB/Rac-protein kinases. Phophorylation is at the Ser site (Km = 3.9 碌M). It also competitively inhibits histone H2B phosphorylation (Ki = 12 碌M) by AKT.
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溶解度
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分子量
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2780.2
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化学式
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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注释
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Documents
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Figures
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Reference
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Jiang, X. et al. Mol. Canc. Ther. 3: 1221 (2004) O?Neill, T. et al. J. Biol. Chem. 277, 16102 (2002 Davies, S. et al. Biochem. J. 351, 95 (2000) Oh, H. et al. Proc. Natl. Acad. Sci. USA 100, 5378 (2003).
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C端
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N端
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化学桥
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