名称
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Insulin B (13 - 23)
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编码
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别名
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Insulin B (13 - 23)
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纯度
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80%,90%,95%,98%,99%
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重量
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1mg,5mg,10mg,50mg,100mg,1g
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序列(单字母缩写)
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EALYLVCGERG
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序列(三字母缩写)
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H-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-OH (trifluoroacetate salt)
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基本描述
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This insulin beta-chain peptide binds to a MHC-II allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic beta cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.
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溶解度
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分子量
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1209.38
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化学式
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C52H84N14O17S1
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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注释
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Documents
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Reference
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C端
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N端
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化学桥
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