| 名称
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[Lys(Ac)382]-p53 (368-393), p53 K382(Ac), biotin-labeled, human
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| 编码
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| 别名
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[Lys(Ac)382]-p53 (368-393), p53 K382(Ac), biotin-labeled, human
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| 纯度
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80%，90%，95%，98%，99%
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| 重量
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1mg,5mg,10mg,50mg,100mg,1g
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| 序列（单字母缩写）
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Biotin-KGGHLKSKKGQSTSRHK-K(Ac)-LMFKTEGPDSD-NH2
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| 序列（三字母缩写）
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Biotin-Lys-Gly-Gly-His-Leu-Lys-Ser-Lys-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys(Ac)-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2(trifluoroacetate salt)
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| 基本描述
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This peptide is derived from amino acid residues 372-389 of human p53 tumor suppressor protein and is acetylated at Lys382. It is biotinylated at its N-terminus through a 6-carbon LC linker. Activated p53 functions to induce cell cycle arrest and apoptosis in response to signals such as DNA damage. Acetylation of p53 reduces ubiquitination by MDM2 and increases p53 half-life in vivo.
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| 溶解度
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| 分子量
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3481
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| 化学式
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| 存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| 注释
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| Documents
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| Figures
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| Reference
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Ghosh, A. et al. Mol. Cell Biol. 24, 7987 (2004)
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| C端
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| N端
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| 化学桥
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