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[Nle4, D-Phe7]-Α-Melanocyte Stimulating Hormone (MSH), Amide
名称
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[Nle4, D-Phe7]-Α-Melanocyte Stimulating Hormone (MSH), Amide
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别名
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αMSH; a-MSH; aMSH; alpha-MSH; alphaMSH;α-Melanocyte Stimulating Hormone; αMelanocyte Stimulating Hormone; a-Melanocyte Stimulating Hormone; aMelanocyte Stimulating Hormone; alpha-Melanocyte Stimulating Hormone; alphaMelanocyte Stimulating Hormone; NDP-MSH[Nle4, D-Phe7]-α-MSH, amide
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序列(单字母缩写)
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Ac-SYSNleEHfRWGKPV-NH2
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序列(三字母缩写)
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Ac-{SER}{TYR}{SER}{NLE}{GLU}{HIS}{d-PHE}{ARG}{TRP}{GLY}{LYS}{PRO}{VAL}-NH2
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C-端
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NH2
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基本描述
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HIV-1 TAT Protein Peptide is known to be a protein and particle transduction domain (PTD) and at the same time to comprise a nuclear localization function (NLS). Oligomers of the TAT (47-57) peptide compact plasmid DNA to nanometric particles and stabilize DNA towards nuclease degradation. At optimized vector compositions, these peptides mediate gene delivery to cells in culture six to eight times more efficiently than poly-L-arginine or the mutant TAT2-M1.
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分子量
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1647.000
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化学式
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C78H111N21O19
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纯度
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> 95%
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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N-端
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Ac
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注释
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[Nle4,DPhe7] alpha-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. [Nle4,DPhe7] alpha-MSH can affect inflammatory and immune responses and peripheral nerve regeneration
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Documents
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Figures
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Reference
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Cragnolini AB, et al. Anxiety-like behavior induced by IL-1beta is modulated by alpha-MSH through central melanocortin-4 receptors. Peptides. Jun 2006; 27(6): 1451-1456.
Yamaoka-Tojo M, et al. Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is upregulated in patients with congestive heart failure. Intern. Med. Jul 2006; 45(7): 429-434.
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