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产品
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[Des-Arg9]-Bradykinin
名称
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[Des-Arg9]-Bradykinin
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别名
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Bk [Des-Arg9]
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序列(单字母缩写)
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RPPGFSPF
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序列(三字母缩写)
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{ARG}{PRO}{PRO}{GLY}{PHE}{SER}{PRO}{PHE}
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基本描述
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Des-Arg9-bradykinin increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Des-Arg9-bradykinin (a B1-receptor agonist) was without activity.
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溶解度
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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分子量
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904.030
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化学式
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C44H61N11O10
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纯度
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> 95%
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存储条件
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Before using, store the peptide in the DRY form at 0 - 5 °C. For and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
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注释
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B1 Receptor Agonist
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Documents
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Figures
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Reference
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Stanisavljevic S, et al. Angiotensin I-converting enzyme inhibitors block protein kinase C epsilon by activating bradykinin B1 receptors in human endothelial cells. J. Pharmacol. Exp. Ther. Mar 2006; 316(3): 1153-1158.
Gera L, et al. Discovery of a dual-function peptide that combines aminopeptidase N inhibition and kinin B1 receptor antagonism. J. Pharmacol. Exp. Ther. Apr 2006; 317(1): 300-308.
El Sayah M, et al. Mechanisms underlying lipopolysaccharide-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro. Mol. Pharmacol. May 2006; 69(5): 1701-1708.
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