服务
产品
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Γ-2-MSH (41-58), Amide
名称
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Γ-2-MSH (41-58), Amide
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别名
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序列(单字母缩写)
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YVMGHFRWDRFG
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序列(三字母缩写)
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{Tyr}{Val}{Met}{Gly}{His}{Phe}{Arg}{Trp}{Asp}{Arg}{Phe}{Gly}
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基本描述
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Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. more of the cells responding to 3-MSH express more than one pituitary hormone mRNA. The effect of 3-MSH is blocked by SHU9119, a MC3R and MC4R antagonist, in only 50% of the responsive cells, suggesting that in half of these cells the mediating receptor is not the MC3R. Low picomolar doses of 3-MSH increase [Ca2+]i in the growth hormone (GH)- and prolactin (PRL)-secreting GH3 cell line.
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分子量
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1570.780
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化学式
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C74H99N21O16S
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纯度
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> 95%
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存储条件
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Store the peptide at -20°C.
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