| 名称
|
Α-Melanocyte-Stimulating Hormone (MSH), Amide
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| 别名
|
α-MSH, amidemelanotropinα-Melanocyte Stimulating Hormone; αMelanocyte Stimulating Hormone; a-Melanocyte Stimulating Hormone; aMelanocyte Stimulating Hormone; alpha-Melanocyte Stimulating Hormone; alphaMelanocyte Stimulating Hormone
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| 序列（单字母缩写）
|
Ac-SYSMEHFRWGKPV-NH2
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| 序列（三字母缩写）
|
Ac-{SER}{TYR}{SER}{MET}{GLU}{HIS}{PHE}{ARG}{TRP}{GLY}{LYS}{PRO}{VAL}-NH2
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| C-端
|
NH2
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| 基本描述
|
Alpha-MSH (alpha melanocyte-stimulating hormone) is an ancient tridecapeptide with potent inhibitory activity in all major forms of inflammation. ACTH has structural similarities to alpha-MSH. ACTH and alpha-MSH can induce grooming, stretching, yawning, penile erection responses in male rats, site of action in the brain and role of melanocortin receptors.
|
| 分子量
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1664.900
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| 化学式
|
C77H109N21O19S1
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| 纯度
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> 95%
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| 存储条件
|
Store the peptide at -20°C. Keep container tightly closed.
|
| N-端
|
Ac
|
| 注释
|
Alpha-MSH is derived from ACTH 1-13. Alpha-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. Alpha-MSH can affect inflammatory and immune responses and peripheral nerve regeneration.
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| Documents
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| Figures
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| Reference
|
Yamaoka-Tojo M, et al. Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is upregulated in patients with congestive heart failure. Intern. Med. Jul 2006; 45(7): 429-434.
Cragnolini AB, et al. Anxiety-like behavior induced by IL-1beta is modulated by alpha-MSH through central melanocortin-4 receptors. Peptides. Jun 2006; 27(6): 1451-1456.
Zhang XQ, et al. Effects of bFGF and alpha-MSH on adhesion and migration of human melanocytes in vitro. Zhejiang Da Xue Xue Bao Yi Xue Ban. Mar 2006; 35(2): 161-164.
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Α-Melanocyte-Stimulating Hormone (MSH), Amide
