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服务
产品  
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 Β-Amyloid (1-40), Rat
| 名称
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Β-Amyloid (1-40), Rat
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| 别名
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| 序列（单字母缩写）
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DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVV
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| 序列（三字母缩写）
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{ASP}{ALA}{GLU}{PHE}{GLY}{HIS}{ASP}{SER}{GLY}{PHE}{GLU}{VAL}{ARG}{HIS}{GLN}{LYS}{LEU}{VAL}{PHE}{PHE}{ALA}{GLU}{ASP}{VAL}{GLY}{SER}{ASN}{LYS}{GLY}{ALA}{ILE}{ILE}{GLY}{LEU}{MET}{VAL}{GLY}{GLY}{VAL}{VAL}
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| 基本描述
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The effect of beta-amyloid-(1-40) was investigated on long-term potentiation of glutamatergic excitatory postsynaptic field potentials recorded in the inner molecular layer in the rat dentate gyrus in vitro. In the presence of 200 nM beta-amyloid-(1-40) there was an increase in long-term potentiation of 51%. Basal synaptic transmission was not affected. These results provide direct evidence that a relatively low concentration of beta-amyloid-(1-40) increases synaptic plasticity.
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| 分子量
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4233.740
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| 化学式
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C190H291N51O57S1
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C.
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| 注释
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HIV-I TAT Protein Peptide
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| Documents
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| Figures
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| Reference
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Head E, et al. Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta. Vaccine. Apr 2006;24(15):2824-2834.
Bazoti FN, et al. Noncovalent Interaction Between Amyloid-beta-Peptide (1-40) and Oleuropein Studied by Electrospray Ionization Mass Spectrometry. J Am Soc Mass Spectrom. Apr 2006;17(4):568-575.
Qin S, et al. System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40. J Neurosci. Mar 2006;26(12):3345-3356.
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