服务
产品
|
Prolactin Releasing Peptide (12-31), Human
名称
|
Prolactin Releasing Peptide (12-31), Humans
|
别名
|
PrRP
|
序列(单字母缩写)
|
TPDINPAWYASRGIRPVGRF-NH2
|
序列(三字母缩写)
|
{THR}{PRO}{ASP}{ILE}{ASN}{PRO}{ALA}{TRP}{TYR}{ALA}{SER}{ARG}{GLY}{ILE}{ARG}{PRO}{VAL}{GLY}{ARG}{PHE}-NH2
|
C-端
|
NH2
|
基本描述
|
PrRP is a member of the structurally related RF-amide family and it has been found in the medulla oblongata, hypothalamus and pituitary. PrRP can cause increases in intracellular calcium and activation of c-Jun N-terminal protein kinase (JNK) in a pertussis toxin insensitive manner; PrRP agonist that stimulates the release of prolactin from the anterior pituitary
|
溶解度
|
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
|
分子量
|
2272.600
|
化学式
|
C104H158N32O26
|
纯度
|
> 95%
|
存储条件
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
注释
|
|
Documents
|
|
Figures
|
|
Reference
|
Laurent P, et al. The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10. Nat. Neurosci. Dec 2005; 8(12): 1735-1741.
Samson WK, Taylor MM. Prolactin releasing peptide (PrRP): an endogenous regulator of cell growth. Peptides. May 2006; 27(5): 1099-1103.
Mera T, et al. Prolactin-releasing peptide is a potent mediator of stress responses in the brain through the hypothalamic paraventricular nucleus. Neuroscience. May 2006; Epub ahead of print.
Romero A., etc. Prolactin-releasing peptide is a potent mediator of the innate immune response in leukocytes from Salmo salar. Vet Immunol Immunopathol. 2012 Jun;147(3-4):170 - 9.
|
|