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服务
产品  
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PGLa
| 名称
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PGLa
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| 别名
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Golyglycolic acid
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| 序列（单字母缩写）
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GMASKAGAIAGKIAKVALKAL-NH2
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| 序列（三字母缩写）
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{GLY}{MET}{ALA}{SER}{LYS}{ALA}{GLY}{ALA}{ILE}{ALA}{GLY}{LYS}{ILE} {ALA}{LYS}{VAL}{ALA}{LEU}{LYS}{ALA}{LEU}-NH2
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| C-端
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NH2
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| 基本描述
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PGLa is an antibiotic peptide found in frog skin. As a member of the magainin family it assumes an amphiphilic α-helical structure upon membrane binding. The cationic peptide has a affinity for bacterial membranes and is able to permeabilize them.
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| 分子量
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1968.460
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| 化学式
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C88H162N26O22S
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C
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| 注释
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| Documents
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| Figures
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| Reference
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Strandberg E, et al. Solid-state NMR analysis of the PGLa peptide orientation in DMPC bilayers: structural fidelity of 2H-labels versus sensitivity of 19F-NMR. Biophys. J. Mar 2006; 90(5): 1676-1686.
Glaser RW, et al. Concentration-dependent realignment of the antimicrobial peptide PGLa in lipid membranes observed by solid-state 19F-NMR. Biophys. J. May 2005; 88(5): 3392-3397.
Kang HS, Han MH et al. Short-term outcome of intracranial aneurysms treated with polyglycolic acid/lactide copolymer-coated coils compared to historical controls treated with bare platinum coils: a single-center experience. AJNR Am J Neuroradiol. Sep 2005;26(8):1921-8.
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