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Peptide YY (PYY), Human
名称
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Peptide YY (PYY), Human
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别名
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PYY
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序列(单字母缩写)
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YPIKPEAPGEDASPEELNRYYASLRHYLNLVTRQRY-NH2
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序列(三字母缩写)
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{TYR}{PRO}{ILE}{LYS}{PRO}{GLU}{ALA}{PRO}{GLY}{GLU}{ASP}{ALA}{SER}{PRO}{GLU}{GLU}{LEU}{ASN}{ARG}{TYR}{TYR}{ALA}{SER}{LEU}{ARG}{HIS}{TYR}{LEU}{ASN}{LEU}{VAL}{THR}{ARG}{GLN}{ARG}{TYR}-NH2
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C-端
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NH2
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基本描述
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Peptide YY (PYY) is mainly found in gastrointestinal tract. It is believed to involve feeding behavior. It is a gut hormone that inhibits both secretin- and cholecystokinin-stimulated pancreatic secretion. This peptide is an endogenous nonselective agonist at NPY receptors.
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分子量
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4309.750
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化学式
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C194H295N55O57
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纯度
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> 95%
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存储条件
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Store the peptide at -20°C. Keep container tightly closed.
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注释
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Documents
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Figures
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Reference
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le Roux CW, et al. Attenuated peptide YY release in obese subjects is associated with reduced satiety. Endocrinology. Jan 2006;147(1):3-8.
Ahituv N, et al. A PYY Q62P variant linked to human obesity. Hum Mol Genet. Feb 1 2006;15(3):387-391.
Kim BJ, et al. Peptide YY is secreted after oral glucose administration in a gender-specific manner. J Clin Endocrinol Metab. Dec 2005;90(12):6665-6671.
Wendy A. Hegefeld., et al. Structural dynamics of neuropeptide hPYY. Biopolymers. 2011 Jul;95(7):487-502.
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