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Parasin I
名称
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Parasin I
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别名
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ParasinI; Parasin 1; Parasin1
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序列(单字母缩写)
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KGRGKQGGKVRAKAKTRSS
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序列(三字母缩写)
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{LYS}{GLY}{ARG}{GLY}{LYS}{GLN}{GLY}{GLY}{LYS}{VAL}{ARG}{ALA}{LYS}{ALA}{LYS}{THR}{ARG}{SER}{SER}
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基本描述
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Parasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). Eighteen of the 19 residues in parasin I are identical to the N-terminus of buforin I, a 39-residue antimicrobial peptide derived from the N-terminus of toad histone H2A. This implies that parasin I is cleaved off of the N-terminus of catfish histone H2A. Parasin I shows strong antimicrobial activity, about 12-100 times as strong as magainin 2, against a wide spectrum of microorganisms, without any hemolytic activity. Furthermore, parasin I shows good antimicrobial activity against fish-specific bacterial pathogens.
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分子量
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2000.300
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化学式
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C82H154N34O24
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纯度
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> 95%
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存储条件
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Store at -20°C
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注释
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