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Neurokinin B
| 名称
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Neurokinin B
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| 别名
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NKB
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| 序列（单字母缩写）
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DMHDFFVGLM-NH2
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| 序列（三字母缩写）
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{ASP}{MET}{HIS}{ASP}{PHE}{PHE}{VAL}{GLY}{LEU}{MET}-NH2
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| C-端
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NH2
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| 基本描述
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Neurokinin B belongs to the tachykinin family. Neurokinin B may play an important role in the olfactory, gustatory, visceral, and neuroendocrine processing information. Neurokinin B is potent bronchioconstrictor and has neruomodulatory roles in various brain functions. Neurokinin B is a member of the tachykinin family of neuropeptides that also includes Substance P and Neurokinin A. These carboxyl terminal-amidated peptides are derived from two preprotachykinin genes - the PPT-A gene encodes the sequences of Substance P, Neurokinin A, and neuropeptide K and the PPT-B gene encodes the sequence of Neurokinin B. Neurokinin B stimulate the production of immunoglobulins in peripheral B lymphocytes, This conditional response to Neurokinin B is likely due NK-3 receptors present only following co-culture and activation.
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| 溶解度
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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| 分子量
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1210.420
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| 化学式
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C55H79N13O14S2
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C.
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| 注释
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Novel mammalian Tachykinin in Porcine spinal cord.
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| Documents
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| Figures
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| Reference
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Cuadrado I, et al. Mapping of neurokinin b in the cat brainstem. Anat. Embryol. (Berl). Sep 2005; 210(2): 133-143.
Duarte CR, et al. Incongruent pattern of neurokinin B expression in rat and mouse brains. Cell Tissue Res. Jan 2006; 323(1): 43-51.
Krajewski SJ, et al. Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence. J. Comp. Neurol. Aug 2005; 489(3): 372-386.
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