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N-Acetyl-Ser-Asp-Lys-Pro
名称
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N-Acetyl-Ser-Asp-Lys-Pro
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别名
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AcSDKP; Ac-S-D-K-P
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序列(单字母缩写)
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SDKP
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序列(三字母缩写)
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{SER}{ASP}{LYS}{PRO}
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基本描述
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Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. Acetyl Ser-Asp-Lys-Pro is also a specific substrate for the N-terminal active site of angiotensin-converting enzyme, which is responsible for its degradation in vivo.
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分子量
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487.500
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化学式
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C20H33N5O9
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纯度
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> 95%
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存储条件
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Store at -20°C.
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N-端
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AC
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注释
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(CFU-S = Spleen Colony-Forming Units) N-Acetyl-Ser-Asp-Lys-Pro exerts a inhibitory activity on the proliferation of hematopoietic pluripotent stem cells
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