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Neuropeptide Y, Human
名称
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Neuropeptide Y, Human
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别名
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NPY
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序列(单字母缩写)
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YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2
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序列(三字母缩写)
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{TYR}{PRO}{SER}{LYS}{PRO}{ASP}{ASN}{PRO}{GLY}{GLU}{ASP}{ALA}{PRO}{ALA}{GLU}{ASP}{MET}{ALA}{ARG}{TYR}{TYR}{SER}{ALA}{LEU}{ARG}{HIS}{TYR}{ILE}{ASN}{LEU}{ILE}{THR}{ARG}{GLN}{ARG}{TYR}-NH2
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C-端
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NH2
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基本描述
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Neuropeptide Y (NPY) is a vasoconstrictor and a brain peptide that inhibits Ca2+-activated K+ channels in vascular smooth muscle. Neuropeptide Y (NPY) is implicated in the control of blood pressure, sexual behavior, and food intake. Neuropeptide Y (NPY) inhibits cholecystokinin- and secretin-stimulated pancreatic secretion.
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溶解度
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Solvent: 1 mg/ml CH3COOH 0.05 M clear, colorless
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分子量
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4271.680
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化学式
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C189H285N55O57S1
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纯度
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> 95%
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存储条件
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Store at -20°C.
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注释
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Documents
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Figures
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Reference
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Thiriet N, et al. Neuropeptide Y protects against methamphetamine-induced neuronal apoptosis in the mouse striatum. J. Neurosci. Jun 2005; 25(22): 5273-5279.
Bromee T, et al. Neuropeptide Y-family receptors Y and Y in chicken. Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region. FEBS. J. May 2006; 273(9): 2048-2063.
Amlal H, et al. Estrogen up-regulates neuropeptide Y Y1 receptor expression in a human breast cancer cell line. Cancer Res. Apr 2006; 66(7): 3706-3714.
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