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Myelin Basic Protein (MBP) (68-82), Guinea Pig
名称
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Myelin Basic Protein (MBP) (68-82), Guinea Pig
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别名
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MBP (68-82), guinea pig
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序列(单字母缩写)
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YGSLPQKSQRSQDEN
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序列(三字母缩写)
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{TYR}{GLY}{SER}{LEU}{PRO}{GLN}{LYS}{SER}{GLN}{ARG}{SER}{GLN}{ASP}{GLU}{ASN}
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基本描述
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Myelin basic protein (MBP)(68-82) induces experimental allergic encephalomyelitis. Myelin basic protein (MBP) is a hydrophilic protein that may function to maintain the correct structure of myelin, interacting with the lipids in the myelin membrane by electrostatic and hydrophobic interactions. Myelin basic protein (MBP) is the target of many post-translational modifications: it is N-terminally acetylated, methylated on an arginine residue, phosphorylated by various serine/threonine protein-kinases, and deamidated on some glutamine residues.
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分子量
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1736.800
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化学式
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C71H113N23O28
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纯度
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> 95%
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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注释
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Documents
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Figures
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Reference
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Polosukhina DI, et al. Metal-dependent hydrolysis of myelin basic protein by IgGs from the sera of patients with multiple sclerosis. Immunol. Lett. Feb 2006; 103(1): 75-81.
Husted C. Structural insight into the role of myelin basic protein in multiple sclerosis. Proc. Natl. Acad. Sci. USA. Mar 2006; 103(12): 4339-4340.
Musse AA, et al. Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope. Proc. Natl. Acad. Sci. USA. Mar 2006; 103(12): 4422-4427.
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