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服务
产品  
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Men 10376
| 名称
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Men 10376
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| 别名
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Neurokinin-2 receptor antagonist
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| 序列（单字母缩写）
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DYWVWWK-NH2
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| 序列（三字母缩写）
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{ASP}{TYR}{d-TRP}{VAL}{d-TRP}{d-TRP}{LYS}-NH2
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| C-端
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NH2
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| 基本描述
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Men 10376 is a potent and selective NK2 tachykinin receptor antagonist. MEN 10376 was devoid of significant agonist activity at i.v. doses (1-3 mumol/kg) which selectively antagonized the effects of an NK-2 agonist [beta-Ala8]-neurokinin A(4-10) (bladder contraction in rats, bronchoconstriction in guinea pigs) without affecting the response to an NK-1 agonist [Sar9]-substance P sulfone (hypotension, salivation and bladder contraction in rats, bronchoconstriction in guinea pigs).
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| 分子量
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1081.220
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| 化学式
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C57H68N12O10
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C. Keep tightly closed.
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| 注释
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