名称
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ll37 (Human)
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别名
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序列(单字母缩写)
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LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
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序列(三字母缩写)
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{LEU}{LEU}{GLY}{ASP}{PHE}{PHE}{ARG}{LYS}{SER}{LYS}{GLU}{LYS}{ILE}{GLY}{LYS}{GLU}{PHE}{LYS}{ARG}{ILE}{VAL}{GLN}{ARG}{ILE}{LYS} {ASP}{PHE}{LEU}{ARG}{ASN}{LEU}{VAL}{PRO}{ARG}{THR}{GLU}{SER}
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基本描述
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The cathelicidin anti-microbial peptide LL-37 is involved in the reepithelialization of human skin wounds and is lacking in chronic ulcer epithelium. LL-37(human) is a cathelicidin-derived peptide with antimicrobial and angiogenic activity.
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溶解度
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Insoluble in water. Dissolve the peptide in 10% acetonitrile with 0.1% TFA solution. Further dilute with desired buffer.
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分子量
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4493.280
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化学式
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C205H340N60O53
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纯度
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> 95%
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存储条件
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Store the product at -20°C. Keep container tightly closed. Store in a cool dry place.
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注释
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Documents
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Figures
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Reference
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Ouhara K, et al. Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, {beta}-defensins and LL37, produced by human epithelial cells. J. Antimicrob. Chemother. Jun 2005; 55(6): 888-896.
Steinstraesser L, et al. The human host defense peptide LL37/hCAP accelerates angiogenesis in PEGT/PBT biopolymers. Annals of plastic surgery. Jan 2006; 56(1): 93-98.
Huang LC, et al. Multifunctional roles of human cathelicidin (LL-37) at the ocular surface.Invest. Ophthalmol. Vis. Sci. Jun 2006; 47(6): 2369-2380.
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